39G171
Benzoic Acid, Crystal, Reagent, ACS, 500g
Q-VD-OPH
Q-VD-OPH, Concentration 100 Percent, Container Size 1mg, Container Material Plastic, Shelf Life No Expiration Date
Артикул:
6LTK9
Каталог:
Grainger
Производитель:
MP BIOMEDICAL
Номер модели:
03OPH10901
Страна производства:
USA
Вес (кг):
0.01
Спецификация:
| Item: Q-VD-OPH |
| Concentration: 100% |
| Container Size: 1mg |
| Container Material: Plastic |
| Shelf Life: No Expiration Date |
| Special Information: The novel Q-VD-OPH compound synthesized using proprietary technology is an irreversible caspase inhibitor specifically designed for in-vivo research.The Q-VD-OPH irreversibily binds to activated Caspases to block apoptosis. Apoptosis is a physiological for of cell death, which plays important role in embryogenesis, cellular homoestasis, tissue atrophy , and removal damaged and mutated cells. Caspases, which acts as molecular chainsaw are the central components of apoptosis response. Caspases are Cysteine proteases that cleave after aspartate residue in their substrates. At least 7 of 14 known mammalian caspases have important role in apoptosis The "OPH" trap with its superior potency, proven cell permeability and minimal toxicity provides an exceptional alternative to the Fluoromethylketone family of inhibitors. These two types of compounds may form the basis for important new drug candidates for a wide variety of disease targets. |